Our Science

The World's Exclusive
Immune Tolerant Exosomes

  • Patented Technology for 5 types of Exosomes
  • Korean Nobel Prize Jang Yeong Sil Science Award
  • 3x Winner of Korea's New Excellent Technology Award
New skincare products

What are exosomes?

Exosomes are nano-sized 'bubbles' (scientifically known as 'extracellular vesicles') that are naturally secreted by all cells of our body.

The role of exosomes is to deliver essential cargo from donor cells to recipient cells.

Did you know?

Each exosome can contain thousands of growth factors protein signals—The important molecules for cell regeneration.

Exosomes can be extracted from plants, animals, and ethical human sources such as amniotic fluid. When exosomes are extracted from stem cells in amniotic fluid, the youngest cells of the body, they acquire its similar regenerative power—without the risks and complications of actually using stem cells.

Simply put, exosomes trigger our aged cells to act young again.

But most exosomes cause immune rejection?

Yes. Despite being nanosized, studies show that standard exosomes used in skincare products today are rejected by our immune system because they do not come from our own body. This results in declining efficacy and the risk of allergic reactions.

Our first breakthrough

Immune Tolerant Exosomes®

Our patented class of exosomes that are uniquely engineered to enter human cells without triggering an immune response. Thanks to a special protein called HLA-G, discovered from our research on how immune tolerance works between mother and fetus during pregnancy.

The safest and most effective exosomes available, setting a new standard in regenerative skincare.

Our second breakthrough

Syn-Exo: Synthetic Exosomes

A groundbreaking advancement in regenerative science, synthetic exosomes are designed to mimic the natural structure and function of exosomes without being derived from living cells.

Unlike natural exosomes, synthetic exosomes can be tailored to carry specific bio-actives—such as growth factors, peptides, and antioxidants—directly to target areas. This customization enhances treatment efficacy and consistency, allowing for hyper-targeted solutions that address individual needs at the cellular level.

RetroEV Skin and Hair Benefits

Key Benefits of Exosomes

RetroEV Skin and Hair Benefits

Skin

  • Boost Collagen and Elastin Production

  • Faster Healing

  • Reduce Scarring and Pigmentation

  • Reduce Inflammation

84%

Reduction in Skin Inflammation

35%

Increased Hydration within 30 minutes

Seamlessly Absorbs Deep Into The Skin

Immune Tolerant Exosomes are naturally designed to penetrate deeply into the dermis and epidermis layers of the skin.

Rapid adsorption happens due to their small size but more importantly, their ability to bypass our immune response.

RetroEV

RETROEV Exosomes

Source: Clinical Skin Penetration Efficacy Test Of RETRO EV® by BioSolution

Hair

  • Improves Scalp Health For Hair Growth

  • Reduces Hair Thinning and Prevents Hair Loss

  • Optimizes the Hair Cycle of Scalp Follicle Cells

24.8%

Increase in Hair Growth Phase

60%

More Prevention of Hair Shedding

* Source: Korean government funded clinical study conducted by Korea Conformity Laboratories

RetroEV Skin and Hair Benefits
RetroEV

Outperforms leading hair loss drug Minoxidil

Clinical study by Korean Conformity Laboratories funded by the Korean government shows IT-Exosomes outperform the leading hair loss drug Minoxidil.

How we innovate

The Exosome Skincare Lab

01 Our Portfolio of Immune Tolerant Exosomes

RETROEV® EXOSOMES

RETROEV® EXOSOMES

PDRN-EXO

PDRN-EXO

CICA-EXO

CICA-EXO

HASUO-EXO

HASUO-EXO

SYNTH-EXO (COMING SOON)

SYNTH-EXO (COMING SOON)

02 Combined With Patented Signature Complexes

Active ingredients

Active ingredients

Active ingredients

Botanical ingredients

03 For Novel skin and Hair Formulas

Active ingredients
Active ingredients
Retro ev

Frequently asked questions

For any other questions, get in touch with us